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VERSION:2.0
PRODID:-//NextToU//EN
CALSCALE:GREGORIAN
BEGIN:VEVENT
UID:094b62cb-c578-44f5-8068-306c751de71b@nexttoyou
DTSTAMP:20261106T174656Z
DTSTART:20261112T161500Z
DTEND:20261112T171500Z
SUMMARY:From SuperAging to preclinical Alzheimer’s disease: how spatial na
 vigation can help uncover mechanisms of cognitive aging
LOCATION:Human Ecology Building T01
DESCRIPTION:Deficits with spatial navigation are a hallmark of healthy agi
 ng\, which can compromise mobility and independence. In addition\, wander
 ing behavior is the second most common behavioral deficit in advanced Alz
 heimer’s disease (AD)\, and path integration has been proposed as a sensi
 tive indicator for detecting patients at increased risk of AD. In this ta
 lk\, I will present a series of studies with human participants combining
  blood biomarker analysis\, immersive virtual reality and functional / mo
 lecular neuroimaging. Using a biologically inspired computational model\,
  I will show how errors in path integration are not only more pronounced 
 in patients with preclinical AD\, but that the sources of error change wi
 th disease progression. Moreover\, I will discuss how compromised grid ce
 ll computations might contribute to deficits in both navigation and episo
 dic memory.\n\nhttp://next-to-u.app/events/094b62cb-c578-44f5-8068-306c75
 1de71b
URL:http://next-to-u.app/events/094b62cb-c578-44f5-8068-306c751de71b
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