BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//NextToU//EN
CALSCALE:GREGORIAN
BEGIN:VEVENT
UID:3129dd57-815f-4654-9f39-61afc707e546@nexttoyou
DTSTAMP:20261106T180110Z
DTSTART:20261112T210000Z
DTEND:20261112T220000Z
SUMMARY:Colloquium on the Brain and Cognition with Julijana Gjorgjieva
LOCATION:Building 46 Singleton Auditorium (46-3002)\, 43 VASSAR ST\, Cambr
 idge\, MA 02139
DESCRIPTION:Time: 4:00pm\nLocation: 46-3002\, Singleton Auditorium (Third 
 floor of MIT Building 46)\n\nTalk Title: How neural circuits acquire stru
 cture and use it flexibly\n\nAbstract: Neural circuits acquire structured
  connectivity during development and learning\, yet must use this organiz
 ation flexibly as sensory inputs\, context and behavioral demands change.
  Understanding how these properties emerge is challenging because multipl
 e plasticity mechanisms\, cell types and synaptic dynamics interact acros
 s spatial and temporal scales. I combine theoretical analysis and mechani
 stic modeling with quantitative analysis of large-scale physiological and
  connectomic data to develop predictive frameworks that link synaptic pla
 sticity\, circuit structure and function across these scales. I will firs
 t discuss how patterned activity and plasticity generate structured organ
 ization from dendritic inputs to recurrent circuits. I will then show how
  inhibitory cell types and short-term synaptic dynamics shape circuit ope
 rating regimes and responses to contextual signals. Finally\, I will disc
 uss how the organization of synaptic inputs on individual dendritic branc
 hes gives rise to dendritic nonlinearities that enable flexible learning 
 without interference between stored representations. Together\, these res
 ults show how local biological mechanisms give rise to circuit-level comp
 utation and motivate the broader goal of understanding how neural circuit
 s are built\, modified by experience and used flexibly to guide \n\nhttp:
 //next-to-u.app/events/3129dd57-815f-4654-9f39-61afc707e546
URL:http://next-to-u.app/events/3129dd57-815f-4654-9f39-61afc707e546
END:VEVENT
END:VCALENDAR