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UID:3d52c0ab-39af-4e74-a012-e67c56278739@nexttoyou
DTSTAMP:20261106T170357Z
DTSTART:20261106T211000Z
DTEND:20261106T221000Z
SUMMARY:Colloquium
LOCATION:Ayres Hall 405\, 1403 Circle Drive\, Knoxville\, TN 37996
DESCRIPTION:Speaker: Dr. Chad Giusti (Oregon State University)\n\nTitle: I
 nvestigating the Topology of Neural Manifolds\n\nAbstract: The last few d
 ecades have seen extraordinary advances in experimental techniques in neu
 roscience. Work in animal models has moved from single electrodes isolati
 ng one or a few neurons to large-scale\, long-term recordings of tens of 
 thousands of neurons or more\, some spanning multiple brain regions or\, 
 in small model organisms such as larval zebrafish\, entire brains. These 
 experiments open the door to questions about how populations of neurons e
 ncode information en masse\, and what neural computation looks like on th
 e macro scale. One fundamental approach to these questions is the study o
 f “neural manifolds\,” low-dimensional structures in the space of populat
 ion activity that are in practice frequently approximated by linear subsp
 aces found via principal component analysis or related methods. Character
 izing the relationship between these structures and presented stimuli or 
 observed behavior has proved very effective at revealing which extrinsic 
 variables are encoded by a population and how its activity evolves over t
 ime.\n\nHowever\, the brain encodes information that naturally carries no
 n-linear structure. Indeed\, two of the most extensively studied brain re
 gions encode inherently circular or toroidal variables. In primary visual
  cortex\, individual neurons are tuned to stimulus orientation. In the hi
 ppocampal formation\, head-direction cells encode heading and grid \n\nht
 tp://next-to-u.app/events/3d52c0ab-39af-4e74-a012-e67c56278739
URL:http://next-to-u.app/events/3d52c0ab-39af-4e74-a012-e67c56278739
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