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UID:852f559b-6450-4805-bfab-48e222ed8394@nexttoyou
DTSTAMP:20261106T175414Z
DTSTART:20261119T223000Z
DTEND:20261119T230000Z
SUMMARY:Neuroscience First Year Presentation: Brodie Woodall
LOCATION:Callier Center Richardson Addition (CRA) 12.110\, 2895 Facilities
  Way\, Richardson\, TX 75080
DESCRIPTION:Please join us\n\nThursday\, November 19\, 2026\n\n4:30pm – 5:
 00pm CST\n\nCRA 12.110\n\nfor a First Year Presentation by\n\nBrodie Wood
 all\n\nUniversity of Texas at Dallas\n\nEukaryotic Initiation Factor 2A R
 egulates Pain Hypersensitivity in Experimental\n\nAutoimmune Encephalomye
 litis\, a Model of Multiple Sclerosis\n\nMultiple Sclerosis (MS) is an au
 toimmune disease of the nervous system characterized by neurodegeneration
 \, demyelination\, and inflammation. Over half of MS patients experience 
 neuropathic pain that is poorly treated. Translation regulation is known 
 to be a contributor to pain pathogenesis\, specifically through the Integ
 rated Stress Response (ISR) and eIF2A-driven translation of stress-resist
 ant genes. We show that eIF2A is elevated in post-mortem human Dorsal Roo
 t Ganglia (DRG) samples and further utilize a mouse model of MS known as 
 Experimental Autoimmune Encephalomyelitis (EAE) to assess the role of eIF
 2A-driven translation in the EAE-induced pain phenotype. Our data establi
 shes a translational approach to uncovering mechanisms of pain in MS and 
 identifies potential avenues for therapeutic developments.\n\nIf you are 
 unable to attend in person\, a Teams link is provided below.\n\nMicrosoft
  Teams meeting\n\nJoin: https://teams.microsoft.com/meet/211383686458232?
 p=kZgpNCtGHj8g0DQH9i\n\nMeeting ID: 211 383 686 458 232\n\nPasscode: bx3d
 7Xa6\n\nhttp://next-to-u.app/events/852f559b-6450-4805-bfab-48e222ed8394
URL:http://next-to-u.app/events/852f559b-6450-4805-bfab-48e222ed8394
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