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UID:a674d447-ea63-423a-b03d-951659439be6@nexttoyou
DTSTAMP:20261106T175404Z
DTSTART:20261119T210000Z
DTEND:20261119T220000Z
SUMMARY:Bioengineering Seminar Series - Dr. Rocky Tuan
LOCATION:Benedum Hall 157\, 3700 O'Hara Street\, Pittsburgh\, PA 15261
DESCRIPTION:Dr. Rocky Tuan\, 8th Vice-Chancellor and President at The Chin
 ese University of Hong Kong\, will present "From Joint Regeneration to Jo
 int-on-a-Chip (miniJoint)."\n\nAbstract\n\nJoint diseases such as osteoar
 thritis (OA) are highly prevalent and represent the primary cause of phys
 ical disability. Despite the success of restorative surgeries\, functiona
 l biological reconstruction of diseased/traumatized articular joint tissu
 es has not been achieved. This unmet medical need is primarily due to ins
 ufficient understanding of disease mechanisms and challenges in engineeri
 ng functionally mature articular joint tissues. Recent technological adva
 nces have led to functional tissue engineering at both the macro- and mic
 ro-scales\, with the former focusing on regenerative implants and the lat
 ter on disease modelling and drug testing. This lecture will provide an o
 verview of the promises and challenges of stem cell- and smart biomateria
 l-based approaches in articular tissue engineering. Specific focus will b
 e on development of the miniJoint\, a human stem cell-derived joint-on-a-
 chip system\, for studying OA pathogenesis\, screening candidate therapeu
 tics\, and analysis of organ/system interactions. These studies illustrat
 e the power of stem cell-based tissue engineering in generating functiona
 l biological implants and physiologically relevant OA models. In particul
 ar\, the emerging tissue/organ-on-a-chip technologies exemplifies a “New 
 Approach Method (NAM)”\, a policy currently advocated by global m\n\nhttp
 ://next-to-u.app/events/a674d447-ea63-423a-b03d-951659439be6
URL:http://next-to-u.app/events/a674d447-ea63-423a-b03d-951659439be6
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